LINFOMA ORBITARIO PDF

Typically patients are between 50 and 70 years of age, with no recognized gender predilection 6. Clinical presentation Clinical presentation is variable as any part of the orbit can be involved. Pathology Orbital lymphoma is a B-cell non-Hodgkin lymphoma , and in most cases arises from mucosa-associated lymphoid tissue i. It is unclear, however, if MALT exists normally in the conjunctiva of the eye, or whether it represents a sequela of inflammation thus the potential link to chlamydial infection. The orbit is otherwise believed to be bereft of lymphatic tissue or lymphatic drainage 1. Non-OAML tumors are of a variety of histologies, with diffuse large B-cell lymphoma being relatively common 4.

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Orbital lymphomas Abstract Ocular adnexa are those structures and tissues surrounding the globe, such as the conjunctiva, the eyelids, the lacrimal gland, extraocular muscles and orbital fat. Most lymphomas occurring in these sites are low-grade b-cell lymphomas.

The most common form of manifestation is by the presence of periorbital edema, a palpable tumor mass, proptosis and diplopia. Biopsy is essential for accurate diagnosis. Most lymphomas of the ocular adnexa are localized at the moment of diagnosis and radiotherapy is a local treatment showing excellent results. Key words: orbital lymphomas, periorbital edema, palpable tumor masses, proptosis, diplopia, Hodgkin. Los LH son extremandamente infrecuentes en los anexos oculares. Figura 1. Figura 2.

TC axial. Tienen una leve preponderancia en mujeres3. Figura 3. TC coronal. Figura 4. Recientes avances incluyeron radioterapia 3D y de intensidad modulada. Referencias Ferry JA et al. Lymphoma of the ocular adnexa: a study of cases. Am J Surg Pathol ; Jakobiec FJ. Ocular adnexal lymphoid tumors: progress in need of clarification. Am J Ophthalmol ; Lymphoproliferative disease of the orbit.

Asia Pac J Ophthalmol Phila ; 4: Verdijk RM. Lymphoproliferative tumors of the ocular adnexa. Asia Pac J Ophthalmol ; 6: Kiesewetter B et al. Clinical features, treatment and outcome of mucosa-associated lymphoid tissue MALT lymphoma of the ocular adnexa: single center experience of 60 patients.

PLoS One ; 9: e Sullivan TJ et al. Lymphoproliferative disease of the ocular adnexa: a clinical and pathologic study with statistical analysis of 69 patients.

Ophthalmic Plast Reconstr Surg ; Primary, unilateral ocular adnexal lymphoma: disease progression and long-term survival. Ophthal Plast Reconstr Surg ; Isaacson P, Wright D. Malignant lymphoma of mucosa associated lymphoid tissue: a distinctive B cell lymphoma. Cancer ; Positron emission tomography in the detection and staging of ocular adnexal lymphoproliferative disease. Ophthalmology ; Preliminary study of positron emission tomography in the detection and management of orbital malignancy.

Suh CO et al. Ejima Y et al. Ocular adnexal mucosa-associated lymphoid tissue lymphoma treated with radiotherapy. Radiother Oncol ; Hoskin PJ et al. Lancet Oncol ; Fasola CE et al. Low-dose radiation therapy 2 Gy x 2 in the treatment of orbital lymphoma. Pinnix CC et al. Ultra-low-dose radiotherapy for definitive management of ocular adnexal B-cell lymphoma. Head Neck ; Savino G et al. Evaluation of intraorbital injection of rituximab for treatment of primary ocular adnexal lymphoma: a pilot study.

Cancer Sci ; Coiffier B et al. N Engl J Med ; Monoclonal antibody treatment of orbital lymphoma. Document Viewer.

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